1. About Us: We are a cutting-edge RNAi therapeutics platform technology startup, focused on developing innovative treatments for various diseases, including COVID-19 and other critical health challenges. Our mission is to rapidly translate groundbreaking scientific discoveries into clinical trials and, ultimately, transformative therapies. 2. Position Summary: As a Research Scientist in Upstream Research, you will play a critical role in advancing our RNA drug development programs. Your work will include but not limited to exosome isolation and characterization, gene and protein expression analysis, cell culture, and the development and characterization of lipid nanoparticles (LNPs) for RNA drug delivery. This position offers the opportunity to be at the forefront of innovative RNA therapeutic development. 3. Key Responsibilities: (1) Cell Engineering and Molecular Biology: • Isolate and characterize exosomes using techniques such as chromatography, dynamic light scattering, and Spectradyne. • Perform gene and protein expression analysis (qRT-PCR, FACS, luciferase assays). • Culture cells and generate stable cell lines, including drug selection. (2) Lipid Nanoparticle Development: • Characterize and manufacture nucleic acid-packaged LNPs using techniques such as chromatography and dynamic light with expertise and interest in lipid nanoparticle (LNP) process development (microfluidic generated LNPs), nucleic acid packaged LNPs, nanoparticle characterization and manufacturing nucleic acid packaged LNPs scattering. (3) General Responsibilities: • Collaborate with cross-functional teams to support R&D activities. • Maintain detailed and accurate records of experiments and results. • Stay updated with the latest scientific advancements in the field of RNA therapeutics. 4. Qualifications: (1) Education: Ph.D. or Master’s degree in Molecular Biology, Biochemistry, Chemistry, Cell Sciences, or a related field. (2) Experience: • Minimum 3+ years (3) Skills: • Excellent problem-solving skills and a keen interest in scientific innovation • Intermediate to proficient in English required